REVIEWS Continuous Infusion Versus Intermittent Bolus Furosemide in ADHF An Updated Meta Analysis of Randomized Control Trials Muhammad Amer MD1 Jurga Adomaityte MD2 Rehan Qayyum MD MHS1 1 Division of General Internal Medicine/Hospitalist Program Johns Hopkins School of Medicine Baltimore Maryland 2Sinai/Johns Hopkins University Internal
May 14 2014 USPharmacist Weekly News Update. May 14 2014. Intermittent PPI Therapy for Bleeding Ulcers Equal to Bolus Continuous Infusion Care Plan. Chicago Intermittent proton pump inhibitor PPI therapy is a less costly treatment and just as effective as the current recommended care plan for managing patients who receive endoscopic treatment for
The mean area under the pH time curve for a 24 hr period was higher for continuous infusion than bolus administration p = .05 . Continuous infusion of famotidine maintained a gastric pH of ≥4 over a longer time period than bolus administration 20.8 hrs vs. 12.6 hrs respectively p <
Continuous infusion versus intermittent bolus injection of propofol during endoscopic retrograde cholangiopancreatography Continuous infusion of propofol during therapeutic ERCP had the advantage over intermittent bolus injection of maintaining a constant level of sedation without increasing adverse events.
Jun 15 2010 Twenty one patients were randomized to bolus injection and 20 patients to continuous infusion. Baseline characteristics were balanced between study arms except for gender with a mean age of 60 / 15 years a mean ejection fraction of 35 / 19 and a mean creatinine level of 1.9 / 1.2 mg/dl.
of administration continuous infusion vs. intermittent bolus for IV diuretics. In a recent publication on unanswered questions in heart failure management over 50 of the
Jul 25 2018 Continuous peripheral nerve blockade provides analgesia for a variety of surgical procedures. For decades there were only three basic local anesthetic administration strategies possible 1 a continuous infusion 2 continuous infusion combined with patient controlled bolus doses and 3 patient controlled bolus doses without a continuous infusion.
Apr 09 2012 Tacrolimus was started at an initial dose of 0.015 mg/kg i.v. bolus administered as a 2 h infusion and then given at every 12 h to maintain a trough drug level between 5–15 ng/mL.
Aug 01 2000 Pharmacokinetic pharmacodynamic evaluation of ceftazidime continuous infusion vs intermittent bolus injection in septicaemic melioidosis B J Angus 1 2 M D Smith 1 2 ‡ Y Suputtamongkol 1 5 H Mattie 3 A L Walsh 1 2 † V Wuthiekanun 1 W Chaowagul 4 and N J White 1 2
Jun 12 2020 There are inconsistent results regarding the efficacy and safety of intermittent epidural bolus IPB versus continuous epidural infusions CPI for labor analgesia. This study used a meta analytic approach to assess the safety and treatment efficacy of IPB versus CPI for labor analgesia based on randomized controlled trials RCTs . Four electronic databases were
Oct 01 2018 Three studies measured the total urine output in the first 24 hours in critically ill patients randomized to treatment with either continuous or bolus intravenous furosemide.10 11 23 The continuous infusion of furosemide resulted in a statistically significant greater urine output in the first 24 hours than the intermittent bolus injection p
The cumulative MTD of the IT was 3.7 mg/kg for continuous infusion and 1.2 mg/kg for intermittent bolus dosing. In addition i.v. infusion of three doses of 275 or 350 μg/kg every other day of RFB4 dsFv PE38 resulted in complete remission CR in all animals. In the case of continuous infusion 100 or 200 μg/kg/day resulted in CR .
Continuous infusions where the next infusion is begun immediately following the completion of the prior may also be used to limit variation in drug concentration in the blood i.e. between the peak drug levels and the trough drug levels . They may also be used instead of intermittent bolus injections for the same reason
Aug 13 2020 Intravenous intermittent infusion is an infusion of a volume of fluid/medication over a set period of time at prescribed intervals and then stopped until the next dose is required. An intermittent IV medication may be called a piggyback medication a secondary medication or a mini bag medication see Figure 7.16 .
Oct 08 2002 Intermittent Bolus Injection versus Continuous Infusion of Furosemide in Normal Adult Greyhound Dogs Darcy B. Adin Aaron W. Taylor Richard C. Hill Karen C. Scott and Frank G. Martin Several studies in human subjects have demonstrated greater diuresis with constant rate infusion CRI furosemide than intermittent bolus IB furosemide.
Sep 16 2019 A larger study on 120 patients receiving TAP block catheters for gastrointestinal surgery randomized to continuous infusion or intermittent bolus by Holmes et al. did not find a significant difference in analgesic outcome between the two modes of delivery either . However the study had a great deal of heterogeneity with potential
Patricia A. McGrath PhD Stephen C. Brown MD in Pain Management Secrets Third Edition 2009 16 Describe the role of continuous infusion in pain management for children. Continuous infusion has several advantages over intermittent SQ IM and IV routes. This method circumvents repetitive injections prevents delays in analgesic drug administration and
Sep 01 1992 At the time of hospital admission patients were randomly assigned to one of two treatment groups. One group four patients received an IV bolus injection of furosemide followed immediately by a continuous infusion for 48 h. The second group five patients was treated with three IV bolus injections a day for 48 h.
Jul 01 2016 Hypertonic saline HTS is used as an adjunct in the conservative management of increased intracranial pressure however the ideal concentration or route of delivery is unknown. Our objective was to assess whether there is a difference in route of delivery bolus versus infusion of 2 versus 3 HTS in patients with traumatic brain injury. The study comprises a
Continuous Infusion versus Intermittent Bolus Injection of Furosemide in Critically Ill Patients A Systematic Review and Meta analysis J Cardiothorac Vasc Anesth . 2018 Oct32 5 2303 2310. doi 10.1053/j.jvca.2018.01.004.
Oct 27 2017 Continuous infusion vs. intermittent bolus injection of furosemide in acute decompensated heart failure systematic review and meta analysis of randomised controlled trials published online September 22 2017 .
Aug 07 2019 A new automated bolus technique for continuous popliteal block A prospective randomized comparison with a continuous infusion technique. Anesth Analg. 1433 7. Taboada M Rodriguez J Bermudez M et al. Comparison of continuous infusion versus automated bolus for postoperative patient controlled analgesia with popliteal
Initial results were promising with two different randomized controlled trials RCTs demonstrating that compared with a continuous infusion intermittent boluses either decreased pain scores or opioid requirements for patients undergoing painful orthopedic foot surgery with sciatic perineural catheters inserted using an insulated needle and
Sep 30 2015 Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Third Trimester Medical Termination of Pregnancy Analgesia a Randomized Study. PCEA IMG PCEA IMG The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
In summary there was no difference between continuous infusion and bolus of furosemide for all cause mortality length of hospital stay and electrolyte disturbance but continuous infusion was superior to bolus administration with regard to diuretic effect and reduction in